-dihydroxyphenyl rings of procyanidin C1 were being located in the composition mimicking K2E2·Pi condition. This interaction results in the ion pathway (which is shaped by residues together with one of the interacting arginines, R979) to become inaccessible in the extracellular side76. This binding mode may Therefore sterically impede ion exchange. https://nepicastat-hydrochloride36790.full-design.com/facts-about-procyanidin-c1-revealed-72296456